Yu-Shao Chen
Chi Mei Medical Center, TaiwanTitle: The role of hyponatremia in predicting urinary tract infection severity
Abstract
Urinary Tract Infection (UTI) is a common disease in pediatrics. UTI patients admitted to the pediatric ward usually have more severe clinical presentation, compared to those treated in the outpatient settings. Therefore, among these patients, it will be helpful to have markers that help predict the severity of the disease and the likelihood of having APN. Only a few studies in the past had suggested hyponatremia to be associated with APN or reflect more severe inflammation in children with febrile UTI. Whether this rarely discussed finding stands true in Taiwanese pediatric population of different age groups (infants, children, and teenagers), deserves further investigation. Therefore, we retrospectively collected blood test, urinalysis, and renal echo result of 344 patients admitted to our pediatric ward for UTI. Patients were assigned to the hyponatremic group and the non-hyponatremic group according to their initial plasma sodium levels obtained upon admission. In the univariate analysis, patients in the hyponatremic group had significantly higher proportion of APN diagnosis, abnormal renal echo findings, and CRP level. By multivariable analysis, hyponatremia was still associated with higher CRP level. These findings show hyponatremia may be another easily obtainable parameter used clinically for determining UTI severity.
Biography
Yu-Shao Chen, M.D. is a pediatric endocrinologist at Chi Mei Medical Center, Tainan, Taiwan. He graduated from the medical school of Tzu Chi University, Hualien, Taiwan. He then completed his pediatric residency and pediatric endocrinology fellowship at Chi Mei Medical Center. His academic interests include pediatric endocrinology and general pediatrics.
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