Background: Liver abscess is characterized as space occupying infectious lesion in the liver parenchyma. Liver abscesses constitute an important cause of morbidity and mortality in children, especially in the developing world. This prospective study was conducted to evaluate the clinical spectrum, diagnostic approach, treatment modalities, and outcomes of children with liver abscesses treated at The Children's Hospital and Institute of Child Health, Faisalabad, Pakistan.

Objectives: To determine the clinical spectrum of liver abscess in Children treated at The Children's Hospital and Institute of Child Health, Faisalabad, Pakistan.

Material and methods: In total, 82 pediatric patients with liver abscesses who presented to our hospital from December 2019 to February 2025 were included. The peculiar nature of this study is the largest sample size of patients among all the studies done until now in our region. Data on age, gender, clinical signs, symptoms, laboratory, and imaging findings were collected and analyzed.

Results: The most common symptoms at presentation were fever (99%), abdominal discomfort (89%), and pain in the right hypochondrium (78%). The diagnosis was pyogenic liver abscess in 48.78%, amoebic abscess in 34.14% and mixed abscess in 14.63% of patients. The most common site of involvement was the right lobe (65.85%). Treatment approaches include conservative management with antibiotics, pigtail catheterization, ultrasound-guided needle aspiration, and surgery. Most patients (80%) resolved in the 2-3-month period, with a few needed >8 months for final resolution.

Conclusion: This study emphasizes the need for early diagnosis, suitable antibiotic therapy, and image-guided drainage in improving the prognosis of pediatric liver abscess. Earlier, the needle aspiration of abscess along with antimicrobial therapy was found to be the main stay of treatment. However, in our study, Catheter drainage was required in most of the patients. Appropriate antibiotic therapy anda timely instituted drainage strategy lead toan excellent treatment response without any mortality.

Nagina deals in liver biopsy, intestinal biopsy, stomach biopsy, and volonic biopsy. Pancreatitis, gallstones. Malnutrition.. Inborn errors of metabolism.. Liver disorders, gastrointestinal disorders, and abdominal tuberculosis. Storage disorders. Spleen disorders. Blood in vomiting. Blood in stools. Esophageal strictures.. Foreign body removal (coin, nail, pin, button battery) via endoscopy. (without stitches, removed with camera). Examination of the small and large intestine. Banding of esophageal varices. Wheat allergy. Milk allergy.