Mauricio Moreno LopezSanta Barbara Hospital, Spain
Title: Plasmatic concentrations of vitamin D in pregnant women during the last trimester and in umbilical cord blood
Fundaments: a raise in vitamin D deficiency has been reported in Spain in recent years, being the health of both mother and newborn also affected by said deficit. The goal of the present work was to evaluate the behavior of vitamin D in the third trimester of pregnancy and in the umbilical cord blood, as well as establish a relation with associated factors in a group of pregnant women in Tomelloso General Hospital, Spain.
Methods: through descriptive and correlational investigation, 346 mother-newborn pairs were evaluated from October 2015 to September 2016. Clinical history data were extracted; mother age, pregnancy age, method of birth, polyvitamin intake, ethnicity, skin phenotype, style of clothing worn, anthropometrical characteristics and gender of newborn. Biochemical variables were determined on the third trimester, and the sample for the umbilical cord was gotten after the pinching, defining deficiency of 25 (OH) D as every value inferior to 20 ng/ml. Intake of calcium and vitamin D was evaluated, as well as solar exposure and skin phototypes. Descriptive and non-parametrical statistics and correlations between variables and groups were applied.
Results: a high percentage of deficiency (72% between severe and moderate deficit) was observed, with adequate vitamin D intake in the majority. In the blood of the umbilical cord was reported a 61,3% deficiency, with a tendency to severe deficit in the winter. There were significances between the levels of vitamin D according to the type of clothing worn, with a higher range average in women who wore regular clothes as opposed to those who covered their head and neck, being the group of pregnant Gypsy and Moroccan women the ones that showed lower values of Vitamin D, despite belonging to countries where solar radiation is very high. There was also correlation between vitamin D and solar exposition, levels of parathohormone, and cord blood vitamin D.
Conclusion: there was a high deficiency of vitamin D both in the mother and in the cord blood, and therefore in the newborns. The necessity to make effective programs from early gestation to prevent severe problems in the mother-newborn duo in public health is.
Mauricio Moreno Lopez, M.S. in pediatric endocrinology from University of Barcelona and neonatology from Valencia Catholic University. He is the chief of pediatrics at Tomelloso General Hospital. He has over 20 publications. He is member of the “Spanish collaborative project for the study of bronchiolitis,” and the “Neonatal Studies Group of Castilla la Mancha”.