Guadalupe Maldonado ColinDr. Manuel Gea Gonzalez General Hospital, Mexico
Title: Langerhans cell histiocytosis presented as persistent diaper dermatitis: A case report
Langerhans cell histiocytosis presents most frequently in pediatric patients with cutaneous manifestations such as erythematous and scaly papules in the trunk or scalp and macerated plaques in intertriginous sites. We present a case of a seven-month-old patient who was brought with complaints of persistent diaper rash. The patient presented with skin fissures in intertriginous areas and pink color papules dispersed widely in the trunk and perineum. The skin biopsy revealed infiltration of abundant histiocytes, eosinophils, lymphocytes, and plasma cells, being CD207, CD1a, and S-100 positive by immunohistochemistry. Due to the diversified presentations of Langerhans cell histiocytosis and its propensity to mimic other dermatological conditions, physicians should have a clinical suspicion of this disease and consider it as a differential diagnosis among common skin diseases in pediatric patients.
Guadalupe Maldonado Colin graduated from the National Autonomous University of Mexico (UNAM) as a Medical Surgeon , later completing a specialty in Pediatrics and a subspecialty in Pediatric Dermatology , at the National Institute of Pediatrics. She is currently assigned to the Dermatology service at the Dr. Manuel Gea Gonzalez General Hospital .She offers consultation at the Star Medical Lomas Verdes Hospital , at the Spanish Hospital and at the ABC Santa Fe Medical Center.