Virtual Conference
Andrey A Garanin

Andrey A Garanin

Samara State Medical University, Russia

Title: Analysis of cardiac manifestations associated with group A B-hemolytic streptococcus


The aim of the study was to study the frequency of ultrasound signs of valvulitis in children who have had streptococcal infection, and the frequency of cases of rheumatic heart disease and acute rheumatic fever.

293 patients aged 6-17 years who had suffered tonsillopharyngitis of streptococcal etiology were examined. All children underwent echocardiography. The structure of morbidity in the adult population was studied with the analysis of data from patients with rheumatic heart disease. According to the results of histological examination, the causes of acquired heart defects were analyzed (n=521).

According to echocardiography, borderline signs of rheumatic heart disease in the form of pathological mitral regurgitation were found in six children; pathological valvular regurgitation – in three; changes in the aortic valve without pathological regurgitation – in two. At the same time, no cases of acute rheumatic fever have been registered among the children's population of polyclinics in the city of Samara for 10 years. The number of adult patients with rheumatic heart disease registered at the dispensary by 2020 was 60. Only one out of 60 people was diagnosed with acute rheumatic fever in adolescence, for which he received bicillin prophylaxis for a year. Analysis of the causes of acquired heart defects based on the results of histological studies after operations for valve replacement revealed the rheumatic nature of the disease in 92 patients (17.6%) out of 521.

There is a discrepancy between the frequency of cases of rheumatic heart disease and acute rheumatic fever, both among adults and children. Echocardiography in the examination of children is a tool for early detection of the rheumatic process. Valvulitis is the most significant manifestation of rheumatic carditis, regardless of the phase of the disease. It is necessary to introduce screening programs based on echocardiography parameters to detect rheumatic heart disease and prevention.